Asia-Pacific Conference on Engineering & Natural Sciences

Okinawa, Japan

July 29-31, 2015,

File 201507-Okinawa Conference Program

Keynote Speaker

Gordon Arbuthnott B.Sc.,Ph.D.


OIST Graduate University, Okinawa, Japan

Topic: Some worries – or excitement – about how the basal ganglia system is –or is NOT - organized.

The organization of human movements is probably the most important function of the brain; think of which aspects of you life would continue without movement!  Many movement disorders seem to have their origin in the basal ganglia – a system of deep brain nuclei below the cortex that seem to be damaged in many motor disorders.

There is a powerful model of this system that has been growing in complexity since it was first described in 1988.  This talk will pose the question – is it time to admit that the model is no longer true?  I will discuss several results that are casting grave doubts on the basic assumptions of the model and on its usefulness in understanding Parkinson’s disease in particular.

If we have time we will also explore some unpublished work that suggests that we have missed an important clue in the structure of the biggest nucleus of the basal ganglia; the striatum.  Recent experiments suggest that there is a hidden substructure in this nucleus that communicates with its neighbors only via long loops including one that contacts the dopamine cells that are most vulnerable in Parkinson’s disease.


Online Submission

Important Dates

Submission Deadline

November 28, 2019

Notification of Acceptance
From December 18, 2019
Registration & Payment Deadline
January 17, 2020
Conference Date
March 17-19, 2020